Match the following new and upcoming rheumatology drugs with their target / mechanism of action... and don't look at the bottom for the answers! Don't worry, I’ll spare you the ones that are nameless and known only by their numbers.
Drugs
1-Fostamatinib
2-Baricitinib
3-Filgotinib
4-Decernotib
5-Ibrutinib
6-Nilotinib
7-Imatinib
8-Mavrilumab
9-Sarilumab
10-Tofacitinib (bonus easy one!)
Mechanism of Action
a-JAK1/JAK2
b-BTK
c-JAK1
d-GM-CSFRa
e-SYK
f-JAK1/JAK3
g-JAK3
h-IL-6R
i-Mast cells
j-TK domain
Answers: 1e; 2a; 3c; 4g; 5b; 6i; 7j; 8d; 9h; 10f
How well did you do? Aren’t you glad these drugs aren't yet marketed!!
Dr. Boulos Haraoui is an Associate Professor of Medicine at the Université de Montréal and head of the Clinical Research Unit. His research interests focus on the diagnosis and management of rheumatoid arthritis.
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